TempoLife › Features › Symptoms and nutrients › frequent-illness
Getting ill often
Catching several colds a winter is normal, particularly for adults living with young children. The nutrients associated with immune function are worth knowing about, and the marketing around them is far ahead of the evidence.
General information only, not a diagnosis. A symptom is not proof of a deficiency — most symptoms here have many possible causes, and the common ones are rarely nutritional. Do not start a supplement to treat a symptom; the safe route is a blood test if one is warranted, and a doctor to interpret it. Use the red-flag list on each page, and see a clinician for anything that persists or worries you.
Start with the base rate, because it reframes the question. Adults typically get a handful of respiratory infections a year, and parents of preschool children get considerably more, because preschool children are efficient distributors of respiratory viruses. Exposure explains most of the variation between people. So does sleep: short sleep is one of the better-replicated risk factors for catching a cold after controlled exposure.
Vitamin C is the most famous immune nutrient and the clearest example of the gap between reputation and evidence. Regular supplementation does not prevent colds in the general population. It does appear to shorten them slightly — by a fraction of a day on average — and there is a specific exception for people undergoing extreme short-term physical stress, such as marathon runners and soldiers in subarctic conditions, in whom prevention trials have been positive. Starting it once you already have symptoms has not shown benefit.
Vitamin D has the more interesting recent story. Meta-analyses of randomised trials have suggested a small protective effect against acute respiratory infection, concentrated in people who were deficient to begin with and in those taking regular rather than large intermittent doses. That is a modest, conditional finding rather than a general recommendation, and it is also why the answer to "should I take vitamin D" in a northern winter is best answered by whoever knows your blood results.
Zinc has evidence for shortening the duration of a common cold when started very early, with meaningful caveats about formulation, dose and side effects — and a specific warning about intranasal zinc products, which have been associated with lasting loss of smell. This is a good example of a nutrient where the delivery route changes the risk entirely.
The unglamorous interventions remain the strongest: sleep, vaccination where it is offered, hand hygiene, and staying home when infectious. If you are getting unusually severe infections, infections that need antibiotics repeatedly, or infections in unusual places, that is a pattern worth investigating rather than supplementing.
Nutrients commonly discussed for frequent illness
Each nutrient below is rated for how strong the evidence is that it relates to this symptom. "Relevant only if you are deficient" means it can matter when your level is genuinely low, but topping it up when it is not low does nothing.
Vitamin D Mixed evidence
Pooled trial data suggest a small protective effect against acute respiratory infection, largest in people who were deficient. A conditional finding, not a general prescription.
| Everyday food | Vitamin D per 100 g |
|---|---|
| Cod liver fish oil | 250 µg |
| Maitake mushrooms, raw | 28.1 µg |
| Greenland halibut, raw | 27.4 µg |
| Mackerel, salted | 25.2 µg |
| Carp, raw | 24.7 µg |
| Eel, raw | 23.3 µg |
Full ranking: foods highest in vitamin d.
Vitamin C Weak evidence
Does not prevent colds in the general population. Slightly shortens them when taken regularly beforehand; no benefit demonstrated when started after symptoms begin. Prevention trials in people under extreme short-term physical stress are the exception.
| Everyday food | Vitamin C per 100 g |
|---|---|
| Acerola, raw | 1678 mg |
| Acerola juice, raw | 1600 mg |
| Yogurt covered candy rolls | 261 mg |
| Green hot chili pepper, raw | 242 mg |
| Guava, raw | 228 mg |
| Silk hazelnut creamer | 200 mg |
Full ranking: foods highest in vitamin c.
Zinc Mixed evidence
Some evidence for shortening a cold when started very early, with real caveats about dose and side effects. Avoid intranasal zinc products entirely — they have been associated with lasting loss of smell.
| Everyday food | Zinc per 100 g |
|---|---|
| Eastern oyster, canned | 91 mg |
| Eastern oyster, fried | 87.1 mg |
| Eastern oyster, raw | 39.3 mg |
| Pacific oyster, cooked | 33.2 mg |
| Incaparina dry mix | 23 mg |
| Quaker Cap'n Crunch's Oops! All Berries | 18 mg |
Full ranking: foods highest in zinc.
Protein Relevant only if you are deficient
Severe protein-energy undernutrition impairs immune function. This is a clinical state, not a description of eating slightly less protein than a target.
Selenium Relevant only if you are deficient
Involved in immune function, and deficiency is uncommon in mixed diets. Worth noting that the gap between an adequate and an excessive selenium intake is narrower than for most nutrients.
| Everyday food | Selenium per 100 g |
|---|---|
| Pork kidney, cooked | 312 µg |
| Lamb kidneys, braised | 219 µg |
| Pork kidney, raw | 190 µg |
| Beef kidneys, simmered | 168 µg |
| Pacific oyster, cooked | 154 µg |
| Beef kidneys, raw | 141 µg |
Full ranking: foods highest in selenium.
Source: Foods richest in each nutrient: USDA FoodData Central SR Legacy (public domain), per 100 g · checked 2026-09-02
Causes that are usually more likely
Before a nutrient, these are the explanations a clinician would normally consider first for frequent illness:
- Exposure — young children, public transport, healthcare and teaching work
- Short or poor sleep
- Smoking and vaping
- Chronic stress
- Asthma, allergy and other airway conditions
- Diabetes and other long-term conditions
- Medicines that suppress the immune system
- Not being up to date with offered vaccinations
When to see a doctor
Treat these as reasons to seek a professional opinion rather than to self-treat:
- Infections that repeatedly need antibiotics or hospital treatment
- Unusual infections, or infections in unusual sites
- Infections alongside unexplained weight loss or night sweats
- Persistent mouth ulcers, thrush or skin abscesses
- A wound or chest infection that will not clear
- Being told your white cell count is abnormal
This list is not exhaustive, and a symptom that is severe, persistent or getting worse always deserves a professional opinion. If you feel very unwell, seek urgent care rather than reading further.
Frequently asked questions
Does vitamin C prevent colds?
Not in the general population. Regular supplementation shortens colds slightly; starting it once symptoms have begun has not shown benefit. Prevention trials have been positive only under extreme short-term physical stress.
How many colds a year is normal?
Several for most adults, and more for parents of young children. Exposure explains most of the difference between people.
Does this symptom mean I have a deficiency?
No. Getting ill often has many possible causes and most are not nutritional. A nutrient link is worth checking with a blood test only when other clues point that way — it is never established by the symptom alone.
Other symptoms
Tiredness and low energy
Tiredness is the most searched symptom on this list and the least specific. It is a normal response to poor sleep, stress and overwork, a feature of dozens of medical conditions, and occasionally the presenting sign of a nutrient deficiency that a blood test would find in minutes.
Hair loss and thinning
Hair shedding has a long list of causes, most of which are not nutritional. The commonest by a wide margin is genetic pattern hair loss, followed by telogen effluvium — a delayed shedding response to a stressor two or three months earlier.
Brittle, splitting or ridged nails
Nails split, peel and ridge for reasons that are mostly mechanical and environmental. Nutrition is in the conversation, but it is well down the list behind water, detergent, solvents and age.
Muscle cramps
Night cramps and exercise cramps are extremely common, and the nutritional explanations attached to them are among the least well supported on this whole page.
Low mood
Low mood is a symptom, not a diagnosis, and the distance between a low week and a depressive illness is a clinical judgement rather than something a checklist can make. This page covers only the nutritional part of a much larger conversation.
Poor concentration and brain fog
"Brain fog" is a description rather than a diagnosis, and it covers everything from a bad night's sleep to the aftermath of an infection to an untreated attention disorder.
All symptoms · Nutrient toplists · Blood test reference ranges
Give a persistent symptom real context
TempoLife tracks sleep, food, activity and mood over time, so when you do see a doctor you bring a record instead of a guess.